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Research in our laboratories concentrates on the adaptation of skeletal and cardiac muscle to various activity models such as exercise (loading) or lack of activity (unloading). Of primary importance to our studies is a phenomenon called muscle plasticity or the changes in muscle due to alterations in quantity and quality (or type) of protein expressed by the muscle. Myosin is a major protein in muscle that acts as both a structural and regulatory protein for muscle function. Therefore myosin and its various forms are a major focus for our research on muscle adaptation.
Our research has implications in several areas including:
- the benefits of exercise and training
- problems associated with extended space flight
- the effects of aging and inactivity on our muscles
Many of our projects are provided with funding awards from the National Institutes of Health (NIH). Our group was also involved in several missions with NASA. These included Space Shuttle flights in which we studied the effects of space flight on skeletal muscle in rats flown aboard the shuttle. We recently began research with the National Space Biomedical Research Institute (NSBRI) which was formed to investigate and solve health issues associated with long term space travel. |
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